Serinol → HCID 23141495, compound

HRID 558427Notes

Reaction equation

HRID 558427 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=2[O:19][CH3:20])[C:13]([OH:15])=O)=[CH:4][CH:3]=1.[NH2:21][CH:22]([CH2:25][OH:26])[CH2:23][OH:24]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5](/[CH:8]=[CH:9]/[C:10]2[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=2[O:19][CH3:20])[C:13]([NH:21][CH:22]([CH2:25][OH:26])[CH2:23][OH:24])=[O:15])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 68294SerinolHCID 23141436HCID 23141436, compound

Product 1

HCID 23141495HCID 23141495, compound

Procedure

The captioned compound was synthesized from 4-methoxy-3-[(E)-2-(4-bromophenyl)vinyl]benzoic acid obtained in step B of Example 2-2-43 and 2-amino-1,3-propanediol in accordance with the same procedure as in the methods described in step C of Example 1-2-3.

Sources & evidence

ORD record
ord-644f91a4f5cc41bfb9172d953e9795f5
Source dataset
uspto-grants-2011_11
Patent number
US08063046B2

Reaction notes

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