HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-1,2-propanediol, (S)- → (S)-N-(2,3-dihydroxy-propyl)-4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-1,2-propanediol, (S)- | HCID 440902 | — |
| Reactant | 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acid | HCID 23141498 | — |
| Product | (S)-N-(2,3-dihydroxy-propyl)-4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]-benzamide | HCID 59265106 | — |
Reaction Steps
The captioned compound was synthesized from 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]-benzoic acid obtained in step B of Example 2-2-1 and (S)-3-amino-1,2-propanediol (produced by Wako Pure Chemical Industries) in accordance with the same procedure as in the methods described in step C of Example 1-2-3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063046B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-3e6008b0d1fd45c08ad80c9d7f831782 |
| Source note | uspto-grants-2011_11 |