HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → 2-Chloro-1,3-thiazole-5-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 2-Chloro-1,3-thiazole-5-sulfonyl chloride | HCID 16228943 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 2-Chloro-1,3-thiazole-5-sulfonamide | HCID 22019518 | 61.4% |
Reaction Steps
Prepared by general procedure III from 2-Chloro-thiazole-5-sulfonyl chloride (1.1 g, 5 mmol) and NH4OH (0.42 mL, 6 mmol) with Et3N (0.77 mL, 6 mmol to give the title compound as a light-brown solid (610 mg, 61%). MS (ISN) 197 [(M−H)−].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063048B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-7457ac211c524596a8dc28bdf371bd63 |
| Source note | uspto-grants-2011_11 |