HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl difluoroacetate → 1,3-Butanedione, 1-(3-ethoxyphenyl)-4,4-difluoro-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl difluoroacetate | HCID 9961 | — |
| Reactant | 1-(3-Ethoxyphenyl)ethanone | HCID 3770250 | — |
| Product | 1,3-Butanedione, 1-(3-ethoxyphenyl)-4,4-difluoro- | HCID 86608012 | 112.1% |
Reaction Steps
Prepared from commercially available ethyl difluoroacetate (16.0 g, 129 mmol) and 3-ethoxyacetophenone (example C.19 step 1) (14.5 g, 88 mmol) as described in example C.1 step 1 to give the title compound (23.90 g, 112%) as a light red oil. MS (ISN) 241.0 [(M−H)−].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063048B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-666c488e512b4564a83ddaed78503299 |
| Source note | uspto-grants-2011_11 |