HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-bromopyridine → 5-(4-Chlorophenyl)pyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-bromopyridine | HCID 70622 | — |
| Reactant | 4-Chlorophenylboronic acid | HCID 74299 | — |
| Product | 5-(4-Chlorophenyl)pyridin-2-amine | HCID 13242644 | — |
Reaction Steps
Prepared from commercially available 2-amino-5-bromopyridine (8.65 g, 50 mmol) and commercially available 4-chlorophenylboronic acid (12.08 g, 77 mmol) as described in example C.20 step 2. Obtained the crude 5-(4-chloro-phenyl)-pyridin-2-ylamine as an orange solid (89% pure).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063048B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-6bf980209f5c465ab56c65fa66f457ee |
| Source note | uspto-grants-2011_11 |