HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1,3-thiazole-5-sulfonic acid → HCID 86608032, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1,3-thiazole-5-sulfonic acid | HCID 13899668 | — |
| Reactant | 3-Ethynyl-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine | HCID 71539732 | — |
| Product | HCID 86608032 | HCID 86608032 | — |
Reaction Steps
The title compound was prepared from 3-ethynyl-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine (example C.1) (355 mg, 1.0 mmol) and 2-bromo-thiazole-5-sulfonic acid (220 mg, 0.9 mmol, prepared according to: Helv. Chim. Acta, 1945, 28, 985) according to general procedure II. Obtained as an orange solid (75 mg, 14%). MS (ISN) 516.8 [(M−H)−]; mp >295° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063048B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-07703246ba9c4ab68c4cc72e26368314 |
| Source note | uspto-grants-2011_11 |