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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 558678Generated: October 29, 2026

HCID 43501995, compound → HCID 11851515, compound

https://huagongshe.com/reaction/558678

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 43501995HCID 43501995—
Reactant3-Ethynyl-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidineHCID 71539732—
ProductHCID 11851515HCID 11851515—

Reaction Steps

The title compound was prepared from 3-ethynyl-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine (example C.1) (150 mg, 0.9 mmol) and 5-Bromo-N-(2-hydroxy-ethyl)-2-methyl-benzenesulfonamide (example B.17) (129 mg, 1.0 mmol) according to general procedure II. Obtained as an orange solid (59 mg, 25%). MS (ISP) 569.2 [(M+H)+]; mp 174-175° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063048B2
Source datasetuspto-grants-2011_11
ORD IDord-a6797975d50b4fcbbe9892e75994d137
Source noteuspto-grants-2011_11