HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-bromo-2-methylbenzenesulfonamide → HCID 11851716, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-bromo-2-methylbenzenesulfonamide | HCID 2446821 | — |
| Reactant | 3-Ethynyl-7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine | HCID 86608034 | — |
| Product | HCID 11851716 | HCID 11851716 | — |
Reaction Steps
The title compound was prepared from 7-Difluoromethyl-3-ethynyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine (example C.2) (340 mg, 1.0 mmol) and 5-bromo-2-fluorobenzenesulfonamide (example B.18) (227 mg, 1.0 mmol) according to general procedure II. Obtained as a yellow solid (220 mg, 43%). MS (ISP) 507.3 [(M+H)+]; mp 265-267° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063048B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-aedc1bb819fa48ba8c49dd130d17ae0d |
| Source note | uspto-grants-2011_11 |