反应详情

(S)-3-(4-Nitro-pyrazol-1-yl)-propane-1,2-diol (29) (180 mg, 10 mmol), and 10% Pd/C (116 mg) in methanol (20 mL) were stirred under hydrogen for at atmospheric pressure and room temperature for 48 h. The reaction mixture was subsequently filtered through celite and concentrated to give A3-2 (160 mg, 100%); LCMS, Rt=0.28 min (MeOH-FA method), m/z 158 (MH+).

1. filtrationThe reaction mixture was subsequently filtered through celite and
2. concentrationconcentrated
3. customto give A3-2 (160 mg, 100%)