HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2,4-difluorobenzenesulfonamide → HCID 86608059, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2,4-difluorobenzenesulfonamide | HCID 2773295 | — |
| Reactant | 5-(4-Chloro-3-methyl-phenyl)-3-ethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine | HCID 86608053 | — |
| Product | HCID 86608059 | HCID 86608059 | — |
Reaction Steps
The title compound was prepared from 5-(4-chloro-3-methyl-phenyl)-3-ethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine (example C.11) (178 mg, 0.5 mmol) and commercially available 5-bromo-2,4-difluoro-benzenesulfonamide (136 mg, 0.5 mmol) according to general procedure II. Obtained as a yellow solid (125 mg, 47%). MS (ISN) 525.2 [(M−H)−]; mp 294° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063048B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-f943c840ffb949269b66bf49cf221392 |
| Source note | uspto-grants-2011_11 |