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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 558897Generated: October 31, 2026

HCID 936105, compound → HCID 16735486, compound

https://huagongshe.com/reaction/558897

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 936105HCID 936105—
Reactant3-Ethynyl-7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidineHCID 86608034—
ProductHCID 16735486HCID 16735486—

Reaction Steps

The title compound was prepared from 7-difluoromethyl-3-ethynyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine (example C.2) (169 mg, 0.5 mmol) and 5-bromo-thiophene-2-sulfonic acid (pyridin-4-ylmethyl)-amide (example B.55) (167 mg, 0.5 mmol) according to general procedure II. Obtained as a yellow solid (96 mg, 33%). MS (ISN) 588.2 [(M−H)−]; mp 141° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063048B2
Source datasetuspto-grants-2011_11
ORD IDord-f789b30388574475a693f14e9df46e5e
Source noteuspto-grants-2011_11