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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 559019Generated: October 25, 2026

3-(2-Methyl-thiazol-4-yl)-phenylamine → 2-((1R,2S)-2-aminocyclohexylamino)-4-(3-(2-methylthiazol-4-yl)phenylamino)pyrimidine-5-carboxamide

https://huagongshe.com/reaction/559019

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-Methyl-thiazol-4-yl)-phenylamineHCID 736535—
Reactant2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[4-(1,2-oxazol-5-yl)anilino]pyrimidine-5-carboxamideHCID 46184612—
Product2-((1R,2S)-2-aminocyclohexylamino)-4-(3-(2-methylthiazol-4-yl)phenylamino)pyrimidine-5-carboxamideHCID 46184368—

Reaction Steps

This compound was synthesised using the synthetic scheme described for the synthesis of compound 122, and using 3-(2-methylthiazol-4-yl)aniline in step 1. MS: 424.37 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063058B2
Source datasetuspto-grants-2011_11
ORD IDord-c6a0257ec4e342ac8c36807466596214
Source noteuspto-grants-2011_11