HCID 57471963, compound → HCID 57471964, compound

HRID 559038Notes

Reaction equation

HRID 559038 reaction equation
[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([C:22]3[CH2:23][CH2:24][O:25][CH2:26][CH:27]=3)[CH:17]=2)[C:12]([C:28]([NH2:30])=[O:29])=[CH:11][N:10]=1>CO.[Pd]>[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:9]1[N:14]=[C:13]([NH:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([CH:22]3[CH2:23][CH2:24][O:25][CH2:26][CH2:27]3)[CH:17]=2)[C:12]([C:28]([NH2:30])=[O:29])=[CH:11][N:10]=1

Participants

4

Reactant 1

HCID 57471963HCID 57471963, compound

Product 1

HCID 57471964HCID 57471964, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The title compound was prepared from Example 175 using standard catalysis hydrogenation by treating the solution of Example 175 in methanol with 10% Pd/C under H2 balloon for overnight. MS found for C22H30N6O2 as (M+H)+ 411.4. UV λ=241, 290 nm.

Sources & evidence

ORD record
ord-4d9ed64fd9e7405eb2850585c109e830
Source dataset
uspto-grants-2011_11
Patent number
US08063058B2

Reaction notes

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