HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium methanolate methanol → 3-Bromo-2-methoxy-6-methyl-pyridine 1-oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium methanolate methanol | HCID 23694274 | — |
| Reactant | 3-Bromo-2-chloro-6-methylpyridin-1-ium-1-olate | HCID 85706489 | — |
| Product | 3-Bromo-2-methoxy-6-methyl-pyridine 1-oxide | HCID 67001239 | — |
Reaction Steps
step b—A solution of 52a (0.5 g) and 0.5 M NaOMe/MeOH (4.9 mL) was stirred at RT overnight. The reaction mixture was concentrated in vacuo and the residue loaded on a SiO2 column and eluted with 5% MeOH/DCM to afford 3-bromo-2-methoxy-6-methyl-pyridine 1-oxide (52b).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063072B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-f15a14dd19e84090bd4768590ff4b7f6 |
| Source note | uspto-grants-2011_11 |