HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → Methyl 2-(5-bromo-6-methoxypyridin-2-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 3-Bromo-2-methoxy-6-methyl-pyridine 1-oxide | HCID 67001239 | — |
| Product | Methyl 2-(5-bromo-6-methoxypyridin-2-yl)acetate | HCID 67001081 | — |
Reaction Steps
step c—A solution of 52b (0.47 g) and acetic anhydride (4.0 mL) was heated at 120° C. for 2 h, The reaction mixture was concentrated in vacuo and purified on a SiO2 column eluting with 5% EtOAc/hexane to afford methyl 5-bromo-6-methoxy-pyridin-2-yl-acetate (52c).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063072B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-511f22a63aa44559a141406aab18419d |
| Source note | uspto-grants-2011_11 |