Methyl iodide → HCID 66997317, compound

HRID 559172Notes

Reaction equation

HRID 559172 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:30](=[O:31])[N:29]([CH3:32])[C:12]2[N:13]([CH3:28])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[CH:24]=[CH:23][N:22]([CH2:25][CH2:26][OH:27])[N:21]=1)=[CH:16][CH:15]=3.I[CH3:34]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:30](=[O:31])[N:29]([CH3:32])[C:12]2[N:13]([CH3:28])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[CH:24]=[CH:23][N:22]([CH2:25][CH2:26][O:27][CH3:34])[N:21]=1)=[CH:16][CH:15]=3

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 66997394HCID 66997394, compound

Product 1

HCID 66997317HCID 66997317, compound

Procedure

The process is carried out as in Example 10 above, using 3-(2,4-dichlorophenyl)-6-[1-(2-hydroxyethyl)-1H-pyrazol-3-yl]-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one from Example 51 and iodomethane.

Sources & evidence

ORD record
ord-952eb3e6ffac40118d11461bb30034e6
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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