4-(2-Chloroethyl)morpholine → HCID 66997908, compound

HRID 559177Notes

Reaction equation

HRID 559177 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:27](=[O:28])[N:26]([CH3:29])[C:12]2[N:13]([CH3:25])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[NH:24][N:23]=[CH:22][CH:21]=1)=[CH:16][CH:15]=3.Cl[CH2:31][CH2:32][N:33]1[CH2:38][CH2:37][O:36][CH2:35][CH2:34]1>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:27](=[O:28])[N:26]([CH3:29])[C:12]2[N:13]([CH3:25])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[CH:21]=[CH:22][N:23]([CH2:31][CH2:32][N:33]2[CH2:38][CH2:37][O:36][CH2:35][CH2:34]2)[N:24]=1)=[CH:16][CH:15]=3

Participants

3

Reactant 2

HCID 767274-(2-Chloroethyl)morpholineHCID 16226262HCID 16226262, compound

Product 1

HCID 66997908HCID 66997908, compound

Procedure

The process is carried out as in Example 36, using compound 3-(2,4-dichlorophenyl)-1,9-dimethyl-6-(1H-pyrazol-5-yl)-1,9-dihydro-2H-pyrido[2,3-b]indol-2-one from Example 39 above and chloroethylmorpholine

Sources & evidence

ORD record
ord-99386d1b6fe44fb5813f11ad4308b9da
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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