Methyl iodide → HCID 66998190, compound

HRID 559187Notes

Reaction equation

[CH2:1]([O:3][C:4]([C:6]1[NH:7][N:8]=[C:9]([C:11]2[CH:12]=[C:13]3[C:17](=[CH:18][CH:19]=2)[N:16]([CH3:20])[C:15]2[N:21]([CH3:34])[C:22](=[O:33])[C:23]([C:25]4[CH:30]=[CH:29][C:28]([Cl:31])=[CH:27][C:26]=4[Cl:32])=[CH:24][C:14]3=2)[CH:10]=1)=[O:5])[CH3:2].I[CH3:36]>>[CH2:1]([O:3][C:4]([C:6]1[N:7]([CH3:36])[N:8]=[C:9]([C:11]2[CH:12]=[C:13]3[C:17](=[CH:18][CH:19]=2)[N:16]([CH3:20])[C:15]2[N:21]([CH3:34])[C:22](=[O:33])[C:23]([C:25]4[CH:30]=[CH:29][C:28]([Cl:31])=[CH:27][C:26]=4[Cl:32])=[CH:24][C:14]3=2)[CH:10]=1)=[O:5])[CH3:2]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 66997990HCID 66997990, compound

Product 1

HCID 66998190HCID 66998190, compound

Procedure

The process is carried out as in Example 36 above, with 5-[3-(2,4-dichlorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]-2H-pyrazole-3-carboxylic acid ethyl ester from Example 43 above and iodomethane.

Sources & evidence

ORD record: ord-5556c1377dc549e5bcbb3a503d01a683
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08063061B2

Reaction notes

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