Hydrazine, ethyl-, ethanedioate (1:1) → HCID 66998376, compound

HRID 559195Notes

Reaction equation

HRID 559195 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:30](=[O:31])[N:29]([CH3:32])[C:11]3[N:12]([CH3:28])[C:13]4[C:18]([C:10]=3[CH:9]=2)=[CH:17][C:16]([C:19](=O)[CH2:20][C:21](=O)[CH2:22][O:23][CH2:24][CH3:25])=[CH:15][CH:14]=4)=[CH:4][CH:3]=1.C(O)(=O)C(O)=O.[CH2:39]([NH:41][NH2:42])[CH3:40]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:30](=[O:31])[N:29]([CH3:32])[C:11]3[N:12]([CH3:28])[C:13]4[C:18]([C:10]=3[CH:9]=2)=[CH:17][C:16]([C:19]2[N:41]([CH2:39][CH3:40])[N:42]=[C:21]([CH2:22][O:23][CH2:24][CH3:25])[CH:20]=2)=[CH:15][CH:14]=4)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 96181Hydrazine, ethyl-, ethanedioate (1:1)HCID 66998060HCID 66998060, compound

Product 1

HCID 66998376HCID 66998376, compound

Procedure

The process is carried out as in Example 37 above, with compound A, 1-[3-(4-fluorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]-4-ethoxy-butane-1,3-dione and ethylhydrazine oxalate.

Sources & evidence

ORD record
ord-c360485e81a242278b528dc0430ad2e6
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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