Methyl iodide → HCID 66998035, compound
Reaction equation
Cl.[Br:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:31](=[O:32])[N:30]([CH3:33])[C:12]3[N:13]([CH3:29])[C:14]4[C:19]([C:11]=3[CH:10]=2)=[CH:18][C:17]([C:20]2[NH:21][N:22]=[C:23]([CH2:25][O:26][CH2:27][CH3:28])[CH:24]=2)=[CH:16][CH:15]=4)=[CH:5][CH:4]=1.Br[C:35]1C=CC(C2C(=O)N(C)C3N(C)C4C(C=3C=2)=CC(C2C=C(COCC)NN=2)=CC=4)=CC=1.IC>>[Br:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:31](=[O:32])[N:30]([CH3:33])[C:12]3[N:13]([CH3:29])[C:14]4[C:19]([C:11]=3[CH:10]=2)=[CH:18][C:17]([C:20]2[CH:24]=[C:23]([CH2:25][O:26][CH2:27][CH3:28])[N:22]([CH3:35])[N:21]=2)=[CH:16][CH:15]=4)=[CH:5][CH:4]=1Participants
4
Procedure
The process is carried out as in Example 36 above, with the compound from Example 84, 3-(4-bromophenyl)-6-(5-ethoxymethyl-1H-pyrazol-3-yl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one and iodomethane.
Sources & evidence
- ORD record
- ord-10a84b28ea3143008b3e790110db856f
- Source dataset
- uspto-grants-2011_11
- Patent number
- US08063061B2
Reaction notes
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