1,3-Dichloroacetone → HCID 66998444, compound

HRID 559210Notes

Reaction equation

HRID 559210 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:24](=[O:25])[N:23]([CH3:26])[C:12]2[NH:13][C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20](=[S:22])[NH2:21])=[CH:16][CH:15]=3.[Cl:27][CH2:28][C:29]([CH2:31]Cl)=O>>[Cl:27][CH2:28][C:29]1[N:21]=[C:20]([C:17]2[CH:18]=[C:19]3[C:14](=[CH:15][CH:16]=2)[NH:13][C:12]2[N:23]([CH3:26])[C:24](=[O:25])[C:9]([C:3]4[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=4[Cl:1])=[CH:10][C:11]3=2)[S:22][CH:31]=1

Participants

3

Reactant 2

HCID 107931,3-DichloroacetoneHCID 86623953HCID 86623953, compound

Product 1

HCID 66998444HCID 66998444, compound

Procedure

The process is carried out as in Example 75, with compound A: 3-(2,4-dichlorophenyl)-1-methyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indole-6-carbothioic acid amide and 1,3-dichloroacetone.

Sources & evidence

ORD record
ord-6c5b8388842f44169f80db433cb3ffb1
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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