Bromomethyl methyl ether → HCID 66998172, compound

HRID 559212Notes

Reaction equation

HRID 559212 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:26](=[O:27])[N:25]([CH3:28])[C:11]3[N:12]([CH3:24])[C:13]4[C:18]([C:10]=3[CH:9]=2)=[CH:17][C:16]([C:19]2[NH:20][N:21]=[CH:22][CH:23]=2)=[CH:15][CH:14]=4)=[CH:4][CH:3]=1.[CH3:29][O:30][CH2:31]Br>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:26](=[O:27])[N:25]([CH3:28])[C:11]3[N:12]([CH3:24])[C:13]4[C:18]([C:10]=3[CH:9]=2)=[CH:17][C:16]([C:19]2[CH:23]=[CH:22][N:21]([CH2:29][O:30][CH3:31])[N:20]=2)=[CH:15][CH:14]=4)=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 83093Bromomethyl methyl etherHCID 66997893HCID 66997893, compoundHCID 178481365HCID 178481365, compound

Product 1

HCID 66998172HCID 66998172, compound

Procedure

The process is carried out as in Example 110 above, using compound from Example 104, 3-(4-chlorophenyl)-1,9-dimethyl-6-(1H-pyrazol-3-yl)-1,9-dihydropyrido[2,3-b]indol-2-one and bromomethyl methyl ether.

Sources & evidence

ORD record
ord-0e326598d2c64758bc788cf6277c963b
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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