2-Amino-2-thioxoethyl 2,2-dimethylpropanoate → 2,2-Dimethylpropionic acid 4-[3-(4-chlorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]thiazol-2-ylmethyl ester

Participants

Role	Name	HCID	Charge
Reactant	2-Amino-2-thioxoethyl 2,2-dimethylpropanoate	HCID 2782113	—
Reactant	6-(2-Bromoacetyl)-3-(4-chlorophenyl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one	HCID 86623954	—
Product	2,2-Dimethylpropionic acid 4-[3-(4-chlorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]thiazol-2-ylmethyl ester	HCID 66998250	—

Reaction Steps

The process is carried out as for Example 8 above, using compound A, 6-(2-bromo-acetyl)-3-(4-chlorophenyl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one and 2-amino-2-thioxoethyl pivalate.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08063061B2
Source dataset	uspto-grants-2011_11
ORD ID	ord-eaaf1bdfd47342c9b96b233698fb0f7e
Source note	uspto-grants-2011_11