Methyl iodide → HCID 66998279, compound

HRID 559222Notes

Reaction equation

HRID 559222 reaction equation
[CH2:1]([O:3][CH2:4][C:5]1[CH:6]=[C:7]([C:10]2[CH:11]=[C:12]3[C:16](=[CH:17][CH:18]=2)[N:15]([CH3:19])[C:14]2[N:20]([CH3:32])[C:21](=[O:31])[C:22]([C:24]4[CH:29]=[CH:28][C:27]([F:30])=[CH:26][CH:25]=4)=[CH:23][C:13]3=2)[NH:8][N:9]=1)[CH3:2].[CH3:33]I>>[CH2:1]([O:3][CH2:4][C:5]1[N:9]([CH3:33])[N:8]=[C:7]([C:10]2[CH:11]=[C:12]3[C:16](=[CH:17][CH:18]=2)[N:15]([CH3:19])[C:14]2[N:20]([CH3:32])[C:21](=[O:31])[C:22]([C:24]4[CH:25]=[CH:26][C:27]([F:30])=[CH:28][CH:29]=4)=[CH:23][C:13]3=2)[CH:6]=1)[CH3:2]

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 66998232HCID 66998232, compoundHCID 178467585HCID 178467585, compound

Product 1

HCID 66998279HCID 66998279, compound

Procedure

The process is carried out as in Example 36 above, with the compound from Example 117, 6-(5-ethoxymethyl-1H-pyrazol-3-yl)-3-(4-fluorophenyl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one and methyl iodide.

Sources & evidence

ORD record
ord-0079054eace14dcbbe2aaed8bcbde401
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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