Pivaloyl chloride → HCID 16226481, compound

HRID 559238Notes

Reaction equation

HRID 559238 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:27](=[O:28])[N:26]([CH3:29])[C:12]2[N:13]([CH3:25])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[NH:21][N:22]=[CH:23][CH:24]=1)=[CH:16][CH:15]=3.[C:30](Cl)(=[O:35])[C:31]([CH3:34])([CH3:33])[CH3:32]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:27](=[O:28])[N:26]([CH3:29])[C:12]2[N:13]([CH3:25])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[CH:24]=[CH:23][N:22]([C:30](=[O:35])[C:31]([CH3:34])([CH3:33])[CH3:32])[N:21]=1)=[CH:16][CH:15]=3

Participants

3

Reactant 2

HCID 62493Pivaloyl chlorideHCID 16226262HCID 16226262, compound

Product 1

HCID 16226481HCID 16226481, compound

Procedure

The process is carried out as indicated in Example 99 above, with the compound from Ex 39, 3-(2,4-dichlorophenyl)-1,9-dimethyl-6-(2H-pyrazol-3-yl)-1,9-dihydro-pyrido[2,3-b]indol-2-one and pivaloyl chloride.

Sources & evidence

ORD record
ord-c3e50558a96e44c69a3fe61e923c95e0
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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