Acetyl chloride → HCID 66998103, compound

HRID 559241Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:21](=[O:22])[N:20]([CH3:23])[C:11]3[N:12]([CH3:19])[C:13]4[C:18]([C:10]=3[CH:9]=2)=[CH:17][CH:16]=[CH:15][CH:14]=4)=[C:4]([F:24])[CH:3]=1.[C:25](Cl)(=[O:27])[CH3:26]>>[C:25]([C:16]1[CH:17]=[C:18]2[C:13](=[CH:14][CH:15]=1)[N:12]([CH3:19])[C:11]1[N:20]([CH3:23])[C:21](=[O:22])[C:8]([C:5]3[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][C:4]=3[F:24])=[CH:9][C:10]2=1)(=[O:27])[CH3:26]

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 66997513HCID 66997513, compound

Product 1

HCID 66998103HCID 66998103, compound

Procedure

The process is carried out as indicated in preparation 1.9B above, with compound A 3-(4-chloro-2-fluorophenyl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one and acetyl chloride.

Sources & evidence

ORD record: ord-c9454f1c865c45cabe38e1de1d82923a
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08063061B2

Reaction notes

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