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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 559249Generated: October 26, 2026

N-Benzyloxycarbonylglycine thioamide → {4-[3-(2,4-dichlorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]thiazol-2-ylmethyl}carbamic acid benzyl ester

https://huagongshe.com/reaction/559249

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-Benzyloxycarbonylglycine thioamideHCID 2756641—
Reactant6-(bromoacetyl)-3-(2,4-dichlorophenyl)-1,9-dimethyl-1,9-dihydro-2H-pyrido[2,3-b]indol-2-oneHCID 86623950—
Product{4-[3-(2,4-dichlorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]thiazol-2-ylmethyl}carbamic acid benzyl esterHCID 66998447—

Reaction Steps

The process is carried out as for Example 8 above, using the compound from preparation 1.2, 6-(bromoacetyl)-3-(2,4-dichlorophenyl)-1,9-dimethyl-1,9-dihydro-2H-pyrido[2,3-b]indol-2-one and N-benzyloxycarbonylglycine thioamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063061B2
Source datasetuspto-grants-2011_11
ORD IDord-41865de17aba489abfb5febf3c7a7eed
Source noteuspto-grants-2011_11