Methanesulfonyl chloride → HCID 66998361, compound

HRID 559251Notes

Reaction equation

HRID 559251 reaction equation
[NH2:1][CH2:2][C:3]1[S:4][CH:5]=[C:6]([C:8]2[CH:9]=[C:10]3[C:14](=[CH:15][CH:16]=2)[N:13]([CH3:17])[C:12]2[N:18]([CH3:31])[C:19](=[O:30])[C:20]([C:22]4[CH:27]=[CH:26][C:25]([Cl:28])=[CH:24][C:23]=4[Cl:29])=[CH:21][C:11]3=2)[N:7]=1.[CH3:32][S:33](Cl)(=[O:35])=[O:34]>>[Cl:29][C:23]1[CH:24]=[C:25]([Cl:28])[CH:26]=[CH:27][C:22]=1[C:20]1[C:19](=[O:30])[N:18]([CH3:31])[C:12]2[N:13]([CH3:17])[C:14]3[C:10]([C:11]=2[CH:21]=1)=[CH:9][C:8]([C:6]1[N:7]=[C:3]([CH2:2][NH:1][S:33]([CH3:32])(=[O:35])=[O:34])[S:4][CH:5]=1)=[CH:16][CH:15]=3

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 669981646-(2-Aminomethylthiazol-4-yl)-3-(2,4-dichlorophenyl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one

Product 1

HCID 66998361HCID 66998361, compound

Procedure

The process is carried out as indicated in Example 99 above, with the compound from Example 147, 6-(2-aminomethylthiazol-4-yl)-3-(2,4-dichlorophenyl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one, and methanesulphonyl chloride.

Sources & evidence

ORD record
ord-15d7046f6ebe4189a6888ec641647145
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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