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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 559257Generated: October 30, 2026

Hydrazine, ethyl-, ethanedioate (1:1) → 3-(2,4-Dichlorophenyl)-9-difluoromethyl-6-(2-ethyl-2H-pyrazol-3-yl)-1-methyl-1,9-dihydropyrido[2,3-b]indol-2-one

https://huagongshe.com/reaction/559257

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine, ethyl-, ethanedioate (1:1)HCID 96181—
Reactant3-(2,4-dichlorophenyl)-9-difluoromethyl-6-((E)-3-dimethylaminoacryloyl)-1-methyl-1,9-dihydropyrido[2,3-b]indol-2-oneHCID 66997927—
Product3-(2,4-Dichlorophenyl)-9-difluoromethyl-6-(2-ethyl-2H-pyrazol-3-yl)-1-methyl-1,9-dihydropyrido[2,3-b]indol-2-oneHCID 66998273—

Reaction Steps

The process is carried out as indicated in Example 37 above, with compound B, 3-(2,4-dichlorophenyl)-9-difluoromethyl-6-((E)-3-dimethylaminoacryloyl)-1-methyl-1,9-dihydropyrido[2,3-b]indol-2-one, and ethylhydrazine oxalate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063061B2
Source datasetuspto-grants-2011_11
ORD IDord-e5b348c6b90545178d31613b78a06126
Source noteuspto-grants-2011_11