Pivaloyl chloride → HCID 66997517, compound

HRID 559268Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:30](=[O:31])[N:29]([CH3:32])[C:12]2[N:13]([CH3:28])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[CH:24]=[C:23]([CH2:25][OH:26])[N:22]([CH3:27])[N:21]=1)=[CH:16][CH:15]=3.[C:33](Cl)(=[O:38])[C:34]([CH3:37])([CH3:36])[CH3:35]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:30](=[O:31])[N:29]([CH3:32])[C:12]2[N:13]([CH3:28])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[CH:24]=[C:23]([CH2:25][O:26][C:33](=[O:38])[C:34]([CH3:37])([CH3:36])[CH3:35])[N:22]([CH3:27])[N:21]=1)=[CH:16][CH:15]=3

Participants

Reactant 2

HCID 62493Pivaloyl chloride

HCID 66998367HCID 66998367, compound2×

Product 1

HCID 66997517HCID 66997517, compound

Procedure

The process is carried out as indicated in Example 70 above, with the compound from Example 82, 3-(2,4-dichlorophenyl)-6-(5-hydroxymethyl-1-methyl-1H-pyrazol-3-yl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one, and pivaloyl chloride.

Sources & evidence

ORD record: ord-3f82057008bd4e5ca83debb68231ecdd
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08063061B2

Reaction notes

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