Pivaloyl chloride → HCID 66998294, compound

HRID 559269Notes

Reaction equation

ClC1C=C(Cl)C=CC=1C1C(=O)N(C)C2N(C)C3C(C=2C=1)=CC(C1NN=CC=1C)=CC=3.[F:31][C:32]1[CH:37]=[CH:36][C:35]([C:38]2[C:57](=[O:58])[N:56]([CH3:59])[C:41]3[N:42]([CH3:55])[C:43]4[C:48]([C:40]=3[CH:39]=2)=[CH:47][C:46]([C:49]2[NH:50][N:51]=[CH:52][C:53]=2[CH3:54])=[CH:45][CH:44]=4)=[CH:34][CH:33]=1.[C:60](Cl)(=[O:65])[C:61]([CH3:64])([CH3:63])[CH3:62]>>[CH3:62][C:61]([CH3:64])([CH3:63])[C:60]([N:51]1[CH:52]=[C:53]([CH3:54])[C:49]([C:46]2[CH:47]=[C:48]3[C:43](=[CH:44][CH:45]=2)[N:42]([CH3:55])[C:41]2[N:56]([CH3:59])[C:57](=[O:58])[C:38]([C:35]4[CH:36]=[CH:37][C:32]([F:31])=[CH:33][CH:34]=4)=[CH:39][C:40]3=2)=[N:50]1)=[O:65]

Participants

Reactant 3

HCID 62493Pivaloyl chloride

HCID 66997872HCID 66997872, compound

HCID 66997918HCID 66997918, compound

Product 1

HCID 66998294HCID 66998294, compound

Procedure

The process is carried out as indicated in Example 70 above, with the compound from Example 53, 3-(4-fluorophenyl)-1,9-dimethyl-6-(4-methyl-2H-pyrazol-3-yl)-1,9-dihydropyrido[2,3-b]indol-2-one, and pivaloyl chloride.

Sources & evidence

ORD record: ord-73bdbcbb8892478397063b0334074f67
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08063061B2

Reaction notes

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