Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isopropenylacetylene → 2-Isopropenyl-1-methanesulfonyl-5-nitro-6-trifluoromethyl-1H-indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isopropenylacetylene | HCID 62323 | — |
| 반응물 | N-[2-Iodo-4-nitro-5-(trifluoromethyl)phenyl]methanesulfonamide | HCID 58979620 | — |
| 생성물 | 2-Isopropenyl-1-methanesulfonyl-5-nitro-6-trifluoromethyl-1H-indole | HCID 58979592 | — |
반응 단계
This compound was prepared using the general Sonagashira conditions as described in general Example C, starting from N-(2-iodo-4-nitro-5-trifluoromethyl-phenyl)-methanesulfonamide (9.0 g, 21.9 mmol) and 2-methyl-1-buten-3-yne (6.25 mL, 65.7 mmol) to yield the title compound as a reddish-brown solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434688B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-963e13d4739c4aaeb3f0eeb94d3d99d9 |
| 출처 메모 | uspto-grants-2016_09 |