HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiazole → HCID 53255816, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | 3-Pentanol | HCID 11428 | — |
| Reactant | 1-Fluoro-2-nitrobenzene | HCID 73895 | — |
| Reactant | 2-(Pentan-3-yloxy)aniline | HCID 17605461 | — |
| Product | HCID 53255816 | HCID 53255816 | 70% |
| Product | N-[2-(3-pentoxy)phenyl]-N'-(thiazol-2-yl)urea | HCID 59732864 | 57% |
Reaction Steps
2-(3-Pentoxy)-1-nitrobenzene (366 mg, 70%) was prepared from 3-pentanol (0.27 ml, 2.5 mmol) and 1-fluoro-2-nitrobenzene (0.36 g, 2.5 mmol) following the general procedure G. This was reduced to 2-(3-pentoxy)aniline (0.25 g, 80%) following general procedure B. N-[2-(3-pentoxy)phenyl]-N′-(thiazol-2-yl)urea (0.26 g, 57%) was prepared from 2-(3-pentoxy)-aniline (0.25 g, 1.5 mmol) and 2-aminothiazole (150 mg, 1.5 mmol) following the general procedure D.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063081B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-a114dd12979a407291d33d07a53d06c9 |
| Source note | uspto-grants-2011_11 |