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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 559947Generated: October 25, 2026

Methyl 3-mercaptopropionate → 3-(2-Amino-thiazol-4-ylmethylsulfanyl)-propionic acid methyl ester

https://huagongshe.com/reaction/559947

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-mercaptopropionateHCID 18050—
Reactant4-Chloromethylthiazol-2-ylamineHCID 73229—
Product3-(2-Amino-thiazol-4-ylmethylsulfanyl)-propionic acid methyl esterHCID 4361762660%

Reaction Steps

3-(2-Amino-thiazol-4-ylmethylsulfanyl)-propionic acid methyl ester (0.75 g, 60%) was prepared from 4-chloromethyl-thiazol-2-ylamine (1.00 g, 5.41 mmol) and 3-mercapto-propionic acid methyl ester (0.97 g, 8.11 mmol) according to procedure Z.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063081B2
Source datasetuspto-grants-2011_11
ORD IDord-69ba71bc44314dbc821031576da39b9e
Source noteuspto-grants-2011_11