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HRID559953

反应详情

EQUATION

反应方程式

HRID 559953 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)C(CS)NC(=O)OC(C)(C)C
HCID4399784

未命名化合物

结构：Cc1ccc(NC(=O)Nc2ncc(Br)s2)c(C(=O)C2CCCC2)c1
HCID59732797

1-(5-Bromothiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-urea

C17H18BrN3O2S

PRODUCTS

生成物

1
结构：COC(=O)C(CSc1cnc(NC(=O)Nc2ccc(C)cc2C(=O)C2CCCC2)s1)NC(=O)OC(C)(C)C
HCID72369977

未命名化合物

收率 35%

PROCEDURE

实验过程

2-tert-Butoxycarbonylamino-3-{2-[3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-ureido]thiazol-5-ylsulfanyl}-propionic acid methyl ester (196 mg, 35%) was prepared from 1-(5-bromo-thiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-urea (408 mg, 1 mmol) and 2-tert-butoxycarbonylamino-3-mercapto-propionic acid methyl ester (470 mg, 2 mmol) following the general procedure Q.