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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 559965Generated: October 30, 2026

HCID 12782766, compound → HCID 59733008, compound

https://huagongshe.com/reaction/559965

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 12782766HCID 12782766—
Reactant1-(5-Bromothiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-ureaHCID 59732797—
ProductHCID 59733008HCID 5973300830%

Reaction Steps

3-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-5-ylsulfanyl}-pyridine-2-carboxylic acid methyl ester (149 mg, 30%) was prepared from 1-(5-bromo-thiazol-2-yl)-3-(2-cyclo pentanecarbonyl-4-methyl-phenyl)-urea (408 mg, 1 mmol) and 3-mercapto-pyridine-2-carboxylic acid methyl ester (340 mg, 2 mmol) following the general procedure Q.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063081B2
Source datasetuspto-grants-2011_11
ORD IDord-e7921e8ea1884a6ea2d595f466faee2d
Source noteuspto-grants-2011_11