Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Mercaptophenylacetic acid → (4-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-5-yl sulfanyl}-phenyl)-acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Mercaptophenylacetic acid | HCID 3390511 | — |
| 반응물 | 1-(5-Bromothiazol-2-yl)-3-(2-cyclopentanecarbonyl-4-methyl-phenyl)-urea | HCID 59732797 | — |
| 생성물 | (4-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-5-yl sulfanyl}-phenyl)-acetic acid | HCID 59733136 | 30% |
반응 단계
(4-{2-[3-(2-Cyclopentanecarbonyl-4-methyl-phenyl)-ureido]-thiazol-5-yl sulfanyl}-phenyl)-acetic acid (140 mg, 30%) was prepared from 1-(5-bromo-thiazol-2-yl)-3-(2-cyclo pentanecarbonyl-4-methyl-phenyl)-urea (408 mg, 1 mmol) and (4-mercapto-phenyl)-acetic acid (336 mg, 2 mmol) following the general procedure Y.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08063081B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-e0d66c6f6d384c64a162497d71a17fd0 |
| 출처 메모 | uspto-grants-2011_11 |