HCID 131736888, compound → HCID 118071683, compound

HRID 56000Notes

Reaction equation

HRID 56000 reaction equation
[Cl:1][C:2]1[C:3]([C:9](=[N:25][O:26][CH3:27])[CH:10]([NH:12][C:13](=[O:24])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[C:20]([F:23])([F:22])[F:21])[CH3:11])=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1>C(#N)C>[Cl:1][C:2]1[C:3](/[C:9](=[N:25]\[O:26][CH3:27])/[CH:10]([NH:12][C:13](=[O:24])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[C:20]([F:22])([F:21])[F:23])[CH3:11])=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1

Participants

3

Reactant 1

HCID 131736888HCID 131736888, compound

Product 1

HCID 118071683HCID 118071683, compoundYield 20.6%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

160 mg of N-[2-(3,5-dichloropyridin-2-yl)-2-methoxyimino-1-methylethyl]-2-(trifluoromethyl)benzamide in 4 ml of acetonitrile was irradiated with light for 12 hours in a quartz cell (manufactured by Fine, 4 clear windows for spectroscopy) using a 100 W high-pressure mercury lamp (manufactured by USHIO INC., lamp: UM-102, power supply: UM-103B-B). After completion of the reaction, the solvent was evaporated under reduced pressure, and the precipitated solid was washed with 5 ml of diisopropyl ether to obtain 33 mg of the desired product as white crystals.

Workup

  1. customAfter completion of the reaction
  2. customthe solvent was evaporated under reduced pressure
  3. washthe precipitated solid was washed with 5 ml of diisopropyl ether

Sources & evidence

ORD record
ord-f2ca6251435a480491268918f5c6eb5a
Source dataset
uspto-grants-2016_09
Patent number
US09434684B2

Reaction notes

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