HCID 67001367, compound → Benzenesulfonyl chloride

HRID 560124Notes

Reaction equation

HRID 560124 reaction equation
[Cl:1]C1C=C([C@H]2[C@@H](C3C=CC=CC=3)CCNC2)C=CC=1.[C:20]1([S:26](N2CC[C@H](C3C=CC=CC=3)[C@H](C3C=CC=C(Cl)C=3)C2)(=[O:28])=[O:27])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[C:20]1([S:26]([Cl:1])(=[O:28])=[O:27])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 67001367HCID 67001367, compoundHCID 131724123HCID 131724123, compound

Product 1

HCID 7369Benzenesulfonyl chloride

Procedure

In analogy to Example 38, from rac-cis-3-(m-chlorophenyl)-4-phenylpiperidine (CAS Reg. No.: [735259-16-2]) and benzenesulfonyl chloride was prepared cis-1-benzenesulfonyl-3-(3-chloro-phenyl)-4-phenyl-piperidine as colorless oil, MS: 412.2 (M+H, 1Cl)+.

Sources & evidence

ORD record
ord-55edbe6cd06947049b6b005a700a732e
Source dataset
uspto-grants-2011_11
Patent number
US08063088B2

Reaction notes

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