Hydrochloric Acid → HCID 67000243, compound

Participants

Reaction Steps

To the above carboxylic acid (13 mg, 0.031 mmol, 1.0 equiv) in methylene chloride (2 mL) at 0° C. was added 0.2 mL of 4 N HCl in dioxane. The reaction was stirred at ambient temperature for 1 h. Then 10 mL of diethyl ether was added to the reaction and the reaction concentrated. To this residue was added 5 mL diethyl ether and the solid was filtered off and washed with diethyl ether several times and air dried for 15 min to provide the title compound (8 mg); MS, electrospray, 313 (M+H).

Provenance & Evidence