Hydrochloric Acid → HCID 66999957, compound

Participants

Reaction Steps

5-(Benzyloxycarbonyl)-amino-3-[3-(t-butoxycarbonylamino)-propyl]-1H-indole-2-carboxylic acid (72 mg) was dissolved in 5 mL of 4 N HCl in dioxane. Within 10 min a white crystalline solid had formed. The mixture was stirred for 45 min at which time the reaction was diluted with 10 mL of methylene chloride. The filtrate was removed with a filter-tipped cannula and the solid was washed 3×10 mL of methylene chloride and dried, providing the title compound; MS, electrospray, 369 (M+H).

Provenance & Evidence