1-Pyrrolidin-1-yl-cyclobutanecarbonitrile → C-Phenyl-C-(1-pyrrolidin-1-yl-cyclobutyl)-methylamine

HRID 560194노트

반응식

HRID 560194 반응식
[N:1]1([C:6]2([C:10]#[N:11])[CH2:9][CH2:8][CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[C:12]1([Li])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[C:12]1([CH:10]([NH2:11])[C:6]2([N:1]3[CH2:5][CH2:4][CH2:3][CH2:2]3)[CH2:7][CH2:8][CH2:9]2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

참가 물질

3

반응물 2

HCID 438027731-Pyrrolidin-1-yl-cyclobutanecarbonitrile2회HCID 178506676HCID 178506676, 화합물

생성물 1

HCID 59197933C-Phenyl-C-(1-pyrrolidin-1-yl-cyclobutyl)-methylamine

실험 절차

The title compound, light yellow liquid, MS: m/e=231.1 [(M+H)+], was prepared in accordance with the general method of intermediate B from 1-pyrrolidin-1-yl-cyclobutanecarbonitrile (intermediate F) and phenyllithium.

출처 및 근거

ORD 기록
ord-5048c69b5bc849c39c33d0fff007dea2
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08063098B2

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