HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-iodobenzene → C-(4-Chloro-phenyl)-C-(1-pyrrolidin-1-yl-cyclobutyl)-methylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-iodobenzene | HCID 12510 | — |
| Reactant | 1-Pyrrolidin-1-yl-cyclobutanecarbonitrile | HCID 43802773 | — |
| Product | C-(4-Chloro-phenyl)-C-(1-pyrrolidin-1-yl-cyclobutyl)-methylamine | HCID 59197928 | — |
Reaction Steps
The title compound, yellow oil, MS: m/e=265.2 [(M+H)+], was prepared in accordance with the general method of intermediate K from 1-pyrrolidin-1-yl-cyclobutanecarbonitrile (intermediate F) and 1-chloro-4-iodobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063098B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-a9902d12065447f69ecd979567ceaa3a |
| Source note | uspto-grants-2011_11 |