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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560202Generated: October 29, 2026

1-Piperidin-1-yl-cyclobutanecarbonitrile → C-Phenyl-C-(1-piperidin-1-yl-cyclobutyl)-methylamine

https://huagongshe.com/reaction/560202

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Piperidin-1-yl-cyclobutanecarbonitrileHCID 43802868—
ReactantHCID 178506676HCID 178506676—
ProductC-Phenyl-C-(1-piperidin-1-yl-cyclobutyl)-methylamineHCID 59197915—

Reaction Steps

The title compound, light yellow liquid, MS: m/e=245.3 [(M+H)+], was prepared in accordance with the general method of intermediate B from 1-piperidin-1-yl-cyclobutanecarbonitrile (intermediate O) and phenyllithium.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063098B2
Source datasetuspto-grants-2011_11
ORD IDord-8c6792bccb0943d0937757578ad56c3a
Source noteuspto-grants-2011_11