1-Fluoro-3-iodobenzene → HCID 59197918, compound

HRID 560205Notes

Reaction equation

HRID 560205 reaction equation
[N:1]1([C:6]2([C:10]#[N:11])[CH2:9][CH2:8][CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[F:12][C:13]1[CH:14]=[C:15](I)[CH:16]=[CH:17][CH:18]=1>>[F:12][C:13]1[CH:18]=[C:17]([CH:10]([NH2:11])[C:6]2([N:1]3[CH2:5][CH2:4][CH2:3][CH2:2]3)[CH2:7][CH2:8][CH2:9]2)[CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 707251-Fluoro-3-iodobenzeneHCID 438027731-Pyrrolidin-1-yl-cyclobutanecarbonitrile2×

Product 1

HCID 59197918HCID 59197918, compound

Procedure

The title compound, yellow, oil, MS: m/e=249.2 [(M+H)+], was prepared in accordance with the general method of intermediate K from 1-pyrrolidin-1-yl-cyclobutanecarbonitrile (intermediate F) and 3-fluoro-iodobenzene.

Sources & evidence

ORD record
ord-6481ea5affce46f4a12238e2f98b4636
Source dataset
uspto-grants-2011_11
Patent number
US08063098B2

Reaction notes

Loading…