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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560207Generated: October 27, 2026

1-Morpholin-4-yl-cyclobutanecarbonitrile → C-(1-Morpholin-4-yl-cyclobutyl)-C-phenyl-methylamine

https://huagongshe.com/reaction/560207

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Morpholin-4-yl-cyclobutanecarbonitrileHCID 43802964—
ReactantHCID 178506676HCID 178506676—
ProductC-(1-Morpholin-4-yl-cyclobutyl)-C-phenyl-methylamineHCID 59197914—

Reaction Steps

The title compound, light yellow liquid, MS: m/e=247.3 [(M+H)+], was prepared in accordance with the general method of intermediate B from 1-morpholin-4-yl-cyclobutanecarbonitrile (intermediate T) and phenyllithium.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063098B2
Source datasetuspto-grants-2011_11
ORD IDord-6636070661f246f0875247db5b5f3a70
Source noteuspto-grants-2011_11