HCID 59197929, compound → HCID 59197905, compound

HRID 560209Notes

Reaction equation

HRID 560209 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:8]2([C:12]#[N:13])[CH2:11][CH2:10][CH2:9]2)[CH2:4][CH2:3]1.[C:14]1([Li])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:8]2([CH:12]([NH2:13])[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH2:11][CH2:10][CH2:9]2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 59197929HCID 59197929, compound2×HCID 178506676HCID 178506676, compound

Product 1

HCID 59197905HCID 59197905, compound

Procedure

The title compound, yellow liquid, MS: m/e=260.2 [(M+H)+], was prepared in accordance with the general method of intermediate B from 1-(4-methyl-piperazin-1-yl)-cyclobutanecarbonitrile (intermediate V) and phenyllithium.

Sources & evidence

ORD record
ord-bc3817b3f14d48cf86091ad786fd2265
Source dataset
uspto-grants-2011_11
Patent number
US08063098B2

Reaction notes

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