Cyclobutanone → HCID 59197910, compound

HRID 560210Notes

Reaction equation

[N:1]1(C2(C#N)COC2)CCC[CH2:2]1.[C:12]1(=O)[CH2:15][CH2:14][CH2:13]1.[NH:17]1[CH2:22][CH2:21][S:20][CH2:19][CH2:18]1>>[N:17]1([C:12]2([C:2]#[N:1])[CH2:15][CH2:14][CH2:13]2)[CH2:22][CH2:21][S:20][CH2:19][CH2:18]1

Participants

Reactant 3

HCID 14496Cyclobutanone

HCID 67164Thiomorpholine

HCID 591979193-Cyano-3-(pyrrolidin-1-YL)oxetane

Product 1

HCID 59197910HCID 59197910, compound

Procedure

The title compound, white solid, MS: m/e=182.9 [(M+H)+], was prepared in accordance with the general method of intermediate A from cyclobutanone and thiomorpholine.

Sources & evidence

ORD record: ord-42eef9e60a9a40debc76c8ebef680dbd
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08063098B2

Reaction notes

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