HCID 59197916, compound → HCID 59197924, compound

HRID 560215Notes

Reaction equation

HRID 560215 reaction equation
[CH:1]1([N:4]2[CH2:9][CH2:8][N:7]([C:10]3([C:14]#[N:15])[CH2:13][CH2:12][CH2:11]3)[CH2:6][CH2:5]2)[CH2:3][CH2:2]1.[C:16]1([Li])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH:1]1([N:4]2[CH2:9][CH2:8][N:7]([C:10]3([CH:14]([NH2:15])[C:16]4[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=4)[CH2:11][CH2:12][CH2:13]3)[CH2:6][CH2:5]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 59197916HCID 59197916, compound2×HCID 178506676HCID 178506676, compound

Product 1

HCID 59197924HCID 59197924, compound

Procedure

The title compound, yellow liquid, MS: m/e=286.2 [(M+H)+], was prepared in accordance with the general method or intermediate B from 1-(4-cyclopropyl-piperazin-1-yl)-cyclobutanecarbonitrile (intermediate V) and phenyllithium.

Sources & evidence

ORD record
ord-447513737ab34037abce18b16e0eec46
Source dataset
uspto-grants-2011_11
Patent number
US08063098B2

Reaction notes

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