Cyclobutanone → HCID 59197938, compound

HRID 560216Notes

Reaction equation

HRID 560216 reaction equation
[N:1]1(C2(C#N)COC2)CCC[CH2:2]1.[C:12]1(=O)[CH2:15][CH2:14][CH2:13]1.C(O)(=O)C(O)=O.[CH2:23]1[C:26]2([CH2:29][NH:28][CH2:27]2)[CH2:25][O:24]1>>[CH2:23]1[C:26]2([CH2:29][N:28]([C:12]3([C:2]#[N:1])[CH2:15][CH2:14][CH2:13]3)[CH2:27]2)[CH2:25][O:24]1

Participants

4

Reactant 3

HCID 14496CyclobutanoneHCID 53308464Oxalic acid--2-oxa-6-azaspiro(3.3)heptane (1/1)HCID 591979193-Cyano-3-(pyrrolidin-1-YL)oxetane

Product 1

HCID 59197938HCID 59197938, compound

Procedure

The title compound was prepared in accordance with the general method of intermediate A from cyclobutanone and 2-oxa-6-aza-spiro[3.3]heptane oxalate (CAS 1045709-32-7).

Sources & evidence

ORD record
ord-56ae0c750d6a4e8ca5d11362cbd35ce1
Source dataset
uspto-grants-2011_11
Patent number
US08063098B2

Reaction notes

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